Gene information
Official symbol IL1R2
Official full name interleukin 1 receptor type 2
Gene type protein-coding gene
Chromosome2q11.2
Alias symbolCD121b
Previous symbolIL1RB
Gene familyCD molecules; Immunoglobulin like domain containing; Interleukin receptors
Resources
Entrez Gene 7850
HGNC HGNC:5994
Ensembl ENSG00000115590
Vega OTTHUMG00000130695
UCSC uc002tbm.4
GO terms: 18 records
GO Description Category LogP Number of genes Detail
GO:0001818 negative regulation of cytokine production GO Biological Processes -48.9957481 97 More
GO:0001959 regulation of cytokine-mediated signaling pathway GO Biological Processes -13.0991884 33 More
GO:0001960 negative regulation of cytokine-mediated signaling pathway GO Biological Processes -11.0318814 22 More
GO:0004896 cytokine receptor activity GO Molecular Functions -9.30297759 21 More
GO:0019221 cytokine-mediated signaling pathway GO Biological Processes -27.5840932 43 More
GO:0019838 growth factor binding GO Molecular Functions -18.6841278 23 More
GO:0019955 cytokine binding GO Molecular Functions -19.1485102 24 More
GO:0030162 regulation of proteolysis GO Biological Processes -41.2267045 73 More
GO:0032650 regulation of interleukin-1 alpha production GO Biological Processes -5.67855223 6 More
GO:0032652 regulation of interleukin-1 production GO Biological Processes -24.2088254 41 More
GO:0032692 negative regulation of interleukin-1 production GO Biological Processes -11.9554195 18 More
GO:0045861 negative regulation of proteolysis GO Biological Processes -27.9905009 43 More
GO:0060759 regulation of response to cytokine stimulus GO Biological Processes -13.7003447 35 More
GO:0060761 negative regulation of response to cytokine stimulus GO Biological Processes -10.5179624 22 More
GO:0071345 cellular response to cytokine stimulus GO Biological Processes -39.647808 70 More
GO:0140375 immune receptor activity GO Molecular Functions -8.53513203 25 More
GO:2000659 regulation of interleukin-1-mediated signaling pathway GO Biological Processes -4.56141436 5 More
GO:2000660 negative regulation of interleukin-1-mediated signaling pathway GO Biological Processes -5.59447366 5 More
KEGG pathways: 1 record
KEGG Description Category LogP Number of genes Detail
hsa04060 Cytokine-cytokine receptor interaction KEGG Pathway -61.0014447 66 More
Drug-Gene interaction
view
Related drugs: 1 record
Drug name Interaction type Source PMID View
anakinra TEND view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
interleukin-1 receptor type 2 proteomics left ventricular remodeling[prognosis (bad)] acute ST elevation myocardial infarction Orrem HL et al. Int J Cardiol. 2018
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